A Florida Invokana Attorney Who Stands Up For Patients' Rights
Invokana and its generic equivalent, canagliflozin, are used to treat Type 2 diabetes. The first diabetes medication of its type, Invokana is manufactured and marketed in the United States by Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson. Invokana is part of a family of medications called SGLT2 inhibitors.
Diabetes is a medical condition that leads to elevated levels of glucose in the bloodstream. Invokana works by preventing glucose from being reabsorbed by the kidneys, which allows the body to excrete that excess glucose in urine. However, this dangerous drug's effects on the kidneys can lead to dangerous and potentially deadly medical conditions.
Invokana and Ketoacidosis
According to a statement released by the Food and Drug Association (FDA) in May 2015, Invokana and other SGLT2 inhibitors are linked to an increased risk of diabetic ketoacidosis (DKA). This is a life-threatening condition in which chemicals called ketones build up in the bloodstream, causing the blood to become acidic. Symptoms of DKA can include:
- Increased thirst
- Increased urination
- Abdominal pain
- Shortness of Breath
- Respiratory Distress
- Loss of Consciousness
If left untreated, diabetic ketoacidosis can cause deadly swelling of the brain.
Unfortunately, Janssen Pharmaceuticals was slow to warn patients and prescribers of the risk of DKA associated with the medication. The original prescribing information mentioned that patients who already had DKA should not take the medication, but there was no information given about the increased risk of developing DKA.
Invokana and Amputations
In May 2017, the FDA issued a “black box warning” – the most serious type of warning – regarding a second serious injury risk linked to Invokana. This warning came following two large clinical trials that showed patients who were given Invokana had twice as many leg and foot amputations as those who were given a placebo.
Again, Janssen failed to conduct adequate monitoring to ensure patient safety and did not adequately warn patients and providers of the risk of amputations. Multiple lawsuits have been filed nationwide by patients who have lost toes, feet and legs due to this dangerous drug.
In addition to ketoacidosis and amputations, Invokana has been shown to have other serious side effects, including hypotension, increased potassium levels and impaired kidney function.
If you or a loved one developed ketoacidosis, had a lower limb amputation or suffered other serious side effects, you may be entitled to compensation. Hold the pharmaceutical companies accountable. Contact a nationally recognized dangerous drug lawyer, Jeffrey D. DeCarlo, today. Call (305) 572-0065 for a free consultation.